From kalilinuxtutorials.com
HyperDbg is designed with a focus on using modern hardware technologies to provide new features to the reverse engineering world. It operates on top of Windows by virtualizing an already running system using Intel VT-x and Intel PT.
This debugger aims not to use any APIs and software debugging mechanisms, but instead, it uses Second Layer Page Table (a.k.a. Extended Page Table or EPT) extensively to monitor both kernel and user executions.