From isc.sans.edu
This project (Malice) provides the ability to have your own locally managed multi-engine malware scanning system. The framework allows the owner to analyze files for known malware. It can be used both as a command tool to analyze samples and review the results via a Kibana web interface. The Command-Line Interface (CLI) is used to scan a file or directory or can be setup to watch and scan new files when copied into a write only directory.
It is modular and is supported by “plugins”. Each plugin (malware scanning engine) can be installed in separate Dockers. Beside AV engines, there are other “plugins” for querying Virustotal (register with a key), hash searches using the NSRL database and Team Cymru.